Table 5.
Gene Ontology-based gene set enrichment analysis functional annotations for high-WSS endothelial cells relative to normal-WSS endothelial cells
| Functional Category | Log2 Expression Ratio (High WSS/Normal WSS) | Adjusted P Value |
|---|---|---|
| Chromosome | 9.98 | 0.011 |
| Cell cycle phase | 9.70 | 0.012 |
| M phase | 9.70 | 0.012 |
| Metalloendopeptidase activity | 9.24 | 0.009 |
| Chromosomal part | 9.18 | 0.009 |
| Mitotic cell cycle | 8.53 | 0.012 |
| Microtubule cytoskeleton | 8.25 | 0.043 |
| M phase of mitotic cell cycle | 8.24 | 0.012 |
| Mitosis | 8.14 | 0.012 |
| Chloride ion binding | 7.89 | 0.012 |
Representative functional gene categories identified from the high-WSS vs. normal-WSS microarray profile using gene set enrichment analysis and the Gene Ontology database. For the complete list, see Supplemental Table S5.