Table 2.
Expression pattern of ASIC and ENaC subunits in different cell and tissue types
ENaC Subunit |
ASIC Subunit |
||||||||
---|---|---|---|---|---|---|---|---|---|
Tissue/Cell | α | β | γ | δ | 1 | 2 | 3 | 4 | Reference No. |
Astrocytes | x | x | x | x | x | x | (40) | ||
BeWo (trophoblast) | x | x | x | (96) | |||||
Bladder | x | x | x | (13, 357) | |||||
Brain | x | x | x | x | x | x | (6, 10, 215, 274, 307) | ||
Chondrocytes, intervertebral discs | x | x | x | x | (203, 388, 389) | ||||
Dorsal root ganglia | x | x | x | x | x | x | (7, 104, 186) | ||
Esophagus | x | x | x | x | x | x | x | (2, 17, 424) | |
Gastrointestinal tract | x | x | x | x | x | x | (64, 103, 117, 133) | ||
Heart neurons | x | x | (167, 373) | ||||||
Inner ear | x | x | x | x | x | (220, 221, 243, 303, 310) | |||
Keratinocytes | x | x | x | (57) | |||||
Kidney | x | x | x | (28) | |||||
Lung, AT1/ ATII cells, bronchus, nasal epithelium, Calu-3 cells | x | x | x | x | x | (27, 116, 211, 212, 371) | |||
Lymphocytes | x | x | x | (441) | |||||
Nodose ganglia | x | x | x | x | x | (258, 372, 423) | |||
Osteoblasts | x | x | x | x | (223) | ||||
Pacinian corpuscles | x | x | (62) | ||||||
Retina | x | x | x | x | x | x | x | x | (56, 149, 277) |
Sperm | x | x | (173) | ||||||
Taste buds | x | x | x | x | x | x | (231, 248, 250, 349) | ||
Uterus, vagina, fallopian tube | x | x | x | (75, 116) | |||||
Vascular smooth muscle | x | x | x | x | x | (156, 205, 206) |