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Effects of reducing transient Na+ current (INa,T) to 70% of its control value in the absence (i) and presence (ii) of INa,L of 6% magnitude on SAN activity using a peripheral SAN cell model. A–F: corresponding effects on APs (A), CLs (B), APDs (C), peak amplitudes (D), (dV/dt)max values (E), and MDPs (F).
