Table 2.
Number of Mice | Sinus Bradycardia | Sinus Tachycardia | Sinus Pause or Arrest | II to III Atrioventricular Block | |
---|---|---|---|---|---|
Baseline | |||||
Ketamine | |||||
WT | 12 | 1/12 | 2/12 | 0/12 | 0/12 |
Scn5a+/ΔKPQ | 10 | 0/10 | 0/10 | 0/10 | 0/10 |
Avertin | |||||
WT | 19 | 1/19 | 0/19 | 0/19 | 0/19 |
Scn5a+/ΔKPQ | 19 | 1/19 | 0/19 | 0/19 | 1/19 |
After pacing | |||||
Ketamine | |||||
WT | 12 | 0/12 | 0/12 | 0/12 | 0/12 |
Scn5a+/ΔKPQ | 10 | 6/10† | 0/10 | 3/10 | 4/10* |
Avertin | |||||
WT | 5 | 0/5 | 0/5 | 0/5 | 0/5 |
Scn5a+/ΔKPQ | 6 | 0/6 | 0/6 | 1/6 | 0/6 |
Values are means ± SE.
P < 0.05 vs. control;
P < 0.01 vs. control.