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. 2012 Jan 27;302(7):H1510–H1523. doi: 10.1152/ajpheart.00357.2011

Table 2.

Frequencies of sinoatrial and atrioventricular node arrhythmic events under ketamine and avertin anesthesia in WT and Scn5a+/ΔKPQ mice

Number of Mice Sinus Bradycardia Sinus Tachycardia Sinus Pause or Arrest II to III Atrioventricular Block
Baseline
Ketamine
    WT 12 1/12 2/12 0/12 0/12
    Scn5a+/ΔKPQ 10 0/10 0/10 0/10 0/10
Avertin
    WT 19 1/19 0/19 0/19 0/19
    Scn5a+/ΔKPQ 19 1/19 0/19 0/19 1/19
After pacing
Ketamine
    WT 12 0/12 0/12 0/12 0/12
    Scn5a+/ΔKPQ 10 6/10 0/10 3/10 4/10*
Avertin
    WT 5 0/5 0/5 0/5 0/5
    Scn5a+/ΔKPQ 6 0/6 0/6 1/6 0/6

Values are means ± SE.

*

P < 0.05 vs. control;

P < 0.01 vs. control.