Fig. 1.
Introgression of a genetic DBA/2J (D2) strain segment onto a pure C57BL/6J strain background reduces ethanol consumption. Shown is mean SEM consumption of 10% ethanol in Chromosome 2 (left) or Chromosome 9 (right) congenic and background strain mice. Introgression of a B6 segment on the alcohol avoiding D2 background did not significantly alter ethanol consumption. Congenic interval: B6.D2 Chromosome 2: 10–86 cM; D2.B6 Chromosome 2: 37–71 cM; both B6.D2 and D2.B6 Chromosome 9: 9–58 cM. *** p < 0.01 for the comparison of B6 to B6.D2 congenic mice