Skip to main content
. 2012 Jan 25;7(4):761–769. doi: 10.1021/cb200450w

Figure 4.

Figure 4

Inhibition of CA-hLysRS interaction by CPs. (a) Binding of Texas Red-labeled hLysRS to CA (100 nM) and WM CA-CTD (inset). (b) Texas Red-labeled CA (100 nM) was preincubated with varying concentrations of CPs (0–8 μM), followed by addition of unlabeled hLysRS (3 μM). (c) Texas Red-labeled WM CA-CTD (100 nM) was preincubated with varying concentrations of CPs (0–8 μM), followed by addition of unlabeled hLysRS (3 μM). (d) GagΔp6 (3 μM) was preincubated with varying amounts of CP1, CP2, and CP4 (0–8 μM) followed by addition of 100 nM FITC-labeled hLysRS.