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The response of 1138H bitransgenic mouse lungs to the induction of FGF-3 for 4 weeks with varying doses of RU486. (A) H&E-stained section of lung from placebo-treated 1138H bitransgenic mouse. (B) H&E-stained section of lungs from 1138H bitransgenic mouse treated with 130 μg/kg RU486. FAMs are abundant. (C) H&E-stained section of lungs from 1138H bitransgenic mouse treated with 200 μg/kg RU486. Type II cell hyperplasia is apparent.
