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. 2012 Jan 4;107(7):1881–1889. doi: 10.1152/jn.00715.2011

Fig. 6.

Fig. 6.

Effect of DCS on population spikes in CA1 neurons stimulated antidromically when DCS current is approximately orthogonal to AP propagation. A: positions of DCS electrodes; Pt-Ir stimulating electrode is touching alveus, and tip of the glass recording electrode is in the CA1 layer. B and C: representative CA1 population spikes before (gray line) and during (black line) 200 μA of anodal and cathodal DCS, respectively. The scaling bars represent 1 mV and 1 ms, respectively. D: effect of DCS on normalized amplitude of the population spikes. Values of the spike amplitude are 38 ± 12, 84 ± 6, 95 ± 2, 100 ± 2, and 81 ± 4% for DCS of −400, −200, −100, +100, and +200 μA, respectively. One-way ANOVA demonstrate significant dependence spike amplitude on the DCS condition, F(4,27) = 14.6 and for P < 0.0001. Numbers of the slices per condition are 6, 7, 6, 7, and 6, respectively. E: effect of DCS on normalized time interval between the stimulus and the population spike. *P < 0.05 and **P < 0.01.