FIG. 7.
XMetA improves insulin tolerance in diabetic mice. A: After 5 weeks of treatment, insulin was administered intraperitoneally at 0.75 units/kg. Blood glucose levels were measured for 120 min in control mice treated with 10 mg/kg isotype control antibody (○) and diabetic mice treated with either 10 mg/kg XMetA (■) or isotype control antibody (●). B: Data normalized to preinsulin glucose values. Values shown are mean ± SEM. *P < 0.05 for diabetic mice treated with XMetA compared with isotype control antibody; n = 8 mice/group.