Table 1.
Clinical samples of the Northeast AIDS Dementia (NEAD) Cohort and the Johns Hopkins CSF Tissue Bank
| Category | Age (years) Avg (dev) | Race (White/Black/Hispanic/Other) | OPN ng/ml mean (Dev) | CD4 cells/ml Mean (Dev) | Plasma viral load log RNA copies/ml Mean (Dev) | CSF viral load log RNA copies/ml mean (Dev) |
|---|---|---|---|---|---|---|
| MSK 0 (n=21) | 39.8 (5.0) | 9/10/2/0 | 7,841 (2244) | 107 (75) | 4.6 (4.8) | 2.5 (2.8) |
| MSK 0.5 (n=35) | 38.3 (5.3) | 10/22/3/0 | 7,862 (3059) | 143 (93) | 5.0 (5.3) | 3.7 (4.1) |
| MSK 1 (n=33) | 43.1 (7.4) | 9/22/1/1 | 7,921 (4734) | 149 (106) | 5.1 (5.7) | 3.2 (3.6) |
| MSK 2 (n=13) | 45.8 (6.4) | 1/12/0/0 | 12,317 (7023) | 110 (100) | 5.4 (5.7) | 3.6 (4.2) |
| Inflammatory (n=30)a | 51.8 (14.8) | 23/6/1 | 5,765 (1471) | n/a | n/a | n/a |
| Non-inflammatory (n=27)b | 43.4 (19.9) | 16/9/1/1 | 4,805 (1558) | n/a | n/a | n/a |
a
Multiple sclerosis (MS), relapsing remitting MS, secondary progressive MS, meningitis, and brachial neuritis
b
Intracranial hypertension, pseudotumor cerebri, hydrocephalus, headaches, and migraine. Avg average, Dev standard deviation, n/a not applicable