Figure 5.

SIRPα is highly expressed on human splenic LCs and is variably detected on primate and rodent sinus lining cells.

Top, left Human LCs as well as the sinus lining cells of MM (old world monkey) (right) express high amounts of SIRPα, whereas expression among SGO (new world monkey) (bottom, left) is more subtle. Most sinus lining cells in rat spleen do not express SIRPα, however, a subpopulation that does express SIRPα can be detected (bottom, right). All images are 200X original magnification