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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Immunol. 2012 Apr 4;188(9):4496–4505. doi: 10.4049/jimmunol.1103086

Figure 7.

Figure 7

The CD8+ splenic LC is an evolutionary newcomer.

Top, left panel. FHOD1 is expressed in sinus lining cells of humans and MM (old world monkey) and man, but cannot be detected in SGO (new world monkey) or in rats. Top, right. CD8 is highly expressed on the sinus lining cells of a Chimpanzee (Hominidae), whereas no CD8 protein is detected on the sinus lining cells of a Baboon (old world monkey). Bottom, summary and diagram of expression patterns that describe LC evolution. All images are magnified 200×.