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. Author manuscript; available in PMC: 2013 Apr 20.
Published in final edited form as: ACS Chem Biol. 2012 Feb 13;7(4):672–677. doi: 10.1021/cb200496y

Figure 4. SR2211 modulates full length RORγ in reporter assays.

Figure 4

293T cells were cotransfected with 5X RORE-luc and either empty vector (A) or RORγ (B); IL-17-Luc reporter and either RORα (C) or RORγ (D); ABCA1 luciferase and LXRα (E) followed by treatment with indicated concentration of SR2211 for 20 hr. The luciferase activity was measured. Relative change was determined by normalizing to vehicle treated cells. Each data point was measured in 4-6 replicates and presented as mean ±SEM.