Table II.

KIR2DL4 mutations

Site	Motifa	KIR Sequenceb	Mutated Sequencec
Segments 1–24			GCAGATCCGC
CRE1	TGACGTCA	TGACGTAG	TAACTTAG; −137, −134
CRE2	TGACGTCA	TGACGTAG	TAATGTAG; −137, −135
MTE/DPE	CSARCSSAAC/RGWYVT	CTGGCAGCAGAAGC	CTGGTAGGAGTAGC; −16, −13 −10
DCE1	AGC (segment 1 of DCE)	AGC	TTT; −15 to −13
DCE2	AGC (segment 1 of DCE)	AGC	ACC; −14
Ets	CMGGAWGYd	ACATCCTC	ACATAATC; −56, −55
dR×1	TGTGGT	TGTGGT	ACTTGT; −100, −99, −97
dR×2	TGTGGT	TGTGGT	TGTTGT; −97
dR×3	TGTGGT	TGTGGT	TGTAGT; −97
pRx	TGTGGT	ACCACA	ATAACA; −62, −61
pRx + Ets	CCACWTCCTd,e	CCACATCCT	TAACATATT; −62, −61, −56, −55
CP2	CNRG(N)5–6 CNRS	CCGGTCAGTCGAGCCGAG	CCGATCATTCGAGCCGAG; −45, −41
MyoD	CANNTG	CAGTCG	TAGTCT; −43, −38
AP1-A	TGASTCA	TGATTCA	GGCTTCA; −161, −159
AP1-B	TGASTCA	TGACTGATTCA	TGTCGGCTGCA, −163, −161, −159, −157
IRF-2	AAANYGAAA	GAAGTGACAA	GAGGTGTCAA; −211, −207
GATA-3	WGATAR	TGATGT	TAACGT; −218, −216

Footnotes:

^aW = A, T; M = A, C; N = A, C, G, T; R = A, G; V =A, C, G; Y = C, T; S = C, G.

^bUnderlining denotes mutation target

^cUnderlining denotes new base at the position indicated

^dReference (56)

^eMotif on antisense strand