Table 2.
Change in Km and Vmax by disruption of microtubule/cytoskeletal structure and PKC inhibitors in GLUT2-IEC cells incubated in 0 to 50mM glucose solutions for 10 minutes.
| Km (mM) |
Vmax (nmol/mg/10-min) |
|
|---|---|---|
| Control | 54.5±11.8 | 2116±278 |
| CAL | 18.7±3.7* | 781±66* |
| CHR | 20.9±3.2* | 1118±76* |
| NOC | 18.5±1.2* | 705±19* |
| CB | 17.0±5.1 | 457±56* |
Differs from Control; P<0.05
NOC, nocodazole; CB, cytochalasin B; CAL, calphostin C; CHR, chelerythrine