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. Author manuscript; available in PMC: 2013 Apr 20.
Published in final edited form as: ACS Chem Biol. 2012 Feb 15;7(4):770–779. doi: 10.1021/cb200536r

Figure 4. (a-d). a. Co-immunoprecipitation of IGF-IR and GIPC in AsPC1 cells.

Figure 4

Figure 4

(a), immunoblot against IGF-IR after immunoprecipitation for GIPC (IP:GIPC/IB:IGF-1R). AsPC1 cells were treated with 200 µM peptide (CR1023 and CR1166) for 24 hours. This immunoblot showed that CR1166 treatment reduces the association between GIPC and IGF-IR more than CR1023 peptide. (b-d). Co-localization of GIPC and IGF-1R using CR1023 and CR1166. (b) Control, (c) treatment with CR1023, and (d) treatment with CR1166, which inhibits the association between GIPC and IGF-1R in AsPC1 cells.