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. Author manuscript; available in PMC: 2013 Apr 20.
Published in final edited form as: ACS Chem Biol. 2012 Feb 15;7(4):770–779. doi: 10.1021/cb200536r

Figure 8. (a-d), In vivo effect of intratumoral injection of peptides on tumor weight, volume, EGFR and IGF-1R expression in breast tumor model.

Figure 8

Figure 8

Figure 8

a. Effect of administration of peptides on the tumor growth over time. b-c. Tumor weight and tumor volumes decreased after peptide treatment, especially CR1166, compared to control peptides. Tumors collected after sacrifice of the SCID mice and measured by digital slide calipers using the (1/2ab2) formula. d. EGFR and IGF-1R expression is decreased in the harvest tumors after CR1166 treatment (T) compared to tumors treated with DMSO alone (U) and CR2055 and CR2059.