Table 3.

Model Fit and Estimates of Direct and Indirect Effect between CVDRFs, Leisure Activities, Inflammatory Markers, and Cognitive Function in Final Trimmed Models

	Total sample (N = 747)	Middle-age group (n = 405)	Old-age group (n = 342)
Model fit	X2 = 36.93, df = 16, p = 0.002; CFI = 0.973; RMSEA = 0.042; SRMR =0.020.	X2 = 30.78, df = 16, p = 0.014; CFI = 0.956; RMSEA = 0.048; SRMR =0.025.	X2 = 26.55, df = 16, p = 0.047; CFI = 0.966; RMSEA = 0.044; SRMR = 0.021.
Direct effect
•CVDRFs – IL-6	0.146	0.136	0.166
•CVDRFs – CRP	0.302	0.331	0.292
•CVDRFs – EM	−0.022	0.060	−0.091
•CVDRFs – EF	−0.060	−0.011	−0.122
•Mental activities – IL-6	0.093	0.010	0.162
•Mental activities – CRP	0.101	0.133	0.086
•Mental activities – EM	0.131	0.137	0.126
•Mental activities – EF	0.279	0.270	0.299
•Physical activities – IL-6	−0.062	−0.048	−0.065
•Physical activities – CRP	−0.117	−0.122	−0.109
•Physical activities – EM	−0.073	0.116	−0.263
•Social activities – EM	−0.029	0.031	−0.096
Interaction with CVDRFs
•Mental activities – IL-6	−0.043	0.005	−0.089
•Physical activities – EM	0.042	−0.036	0.125

Note. Note. Age and sex were covariates of inflammatory markers and cognitive function; education and depression were covariates of cognitive function. Bold data indicate significant estimates. EM = Episodic memory; EF = Executive function.