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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Immunol. 2012 Mar 26;188(9):4527–4534. doi: 10.4049/jimmunol.1103652

Figure 3. RvE2 enhances non-phlogistic actions of human macrophages: increases in phagocytosis and IL-10.

Figure 3

A) RvE2 enhances human macrophage phagocytosis. Macrophages were exposed to different concentrations of RvE2 for 15 minutes (at 37°C, pH 7.45), then FITC-labeled opsonized zymosan was added and incubated for 30 minutes. Particles that were not phagocytized were washed and quenched with trypan blue. Results are shown as % enhancement of phagocytosis above vehicle treatment. B) RvE2 enhances IL-10 production by human macrophages. Macrophages were incubated with different doses of RvE2 for one hour and then exposed to LPS (100 ng/mL). Supernatants were collected 24 hours later and IL-10 level was measured. Results are n≥3 for each concentration and are representative of 4 similar datasets from individual donors. *p<0.05.