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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Immunol. 2012 Mar 30;188(9):4468–4475. doi: 10.4049/jimmunol.1102643

Figure 2. NK cell cytotoxicity against MHC class I-deficient and NKG2D ligand expressing targets in mouse model of COPD.

Figure 2

(A) Representation of flow cytometry analysis comparing in vivo clearance. CFSE labeled C57BL/6 (CFSE low) cells and C57BL/6 B2m-/- (CFSE high) cells were injected i.v .into receipt mice exposed to exposed to FA or CS. Mice were bled 16 hrs following injections and labeled target cells were analyzed by flow cytometry. (B) Time course of NK cell cytotoxicity against B2m-/- target cells, as described in (A), in mice exposed to FA or CS for 3-10 months. Data representative of results from four independent experiments.