Table 2.

Significant findings regarding the comparison of outcomes between treatment groups (intent-to-treat) controlling for baseline value, age, race, education and site¹

		Month 12		Month 18
Outcomes	Comparison b	Estimate	p-value	Estimate	p-value
Symptom Experience c
Total Symptom Number (0–14)	(A v C) SD v C	0.29	0.531	−0.57	0.039
	(B v C) G v C	0.19	0.915	−0.04	0.369
	(A v B) SD v G	0.10	0.622	−0.53	0.258
Total Symptom Frequency (0–70)	(A v C) SD v C	0.65	0.284	−1.24	0.093
	(B v C) G v C	1.44	0.931	0.92	0.709
	(A v B) SD v G	−0.79	0.293	−2.17	0209
Total Symptom Bother (0–70)	(A v C) SD v C	0.90	0.339	−2.31	0.017
	(B v C) G v C	0.65	0.484	0.18	0.269
	(A v B) SD v G	0.25	0.788	−2.49	0.210
Cardiac Symptoms
Number of Common Cardiac Symptoms (0–5)	(A v C) SD v C	0.03	0.783	−0.22	0.016
	(B v C) G v C	−0.04	0.412	−0.03	0.546
	(A v B) SD v G	0.07	0.606	−0.19	0.060
Frequency of Common Cardiac Symptoms (0–25)	(A v C) SD v C	0.03	0.724	−0.55	0.033
	(B v C) G v C	0.03	0.494	0.18	0.915
	(A v B) SD v G	0.00	0.746	−0.73	0.044
Bother with Common Cardiac Symptoms (0–25)	(A v C) SD v C	0.30	0.905	−0.73	0.018
	(B v C) G v C	−0.07	0.337	0.07	0.515
	(A v B) SD v G	0.37	0.421	−0.81	0.071
6-minute walk distance (ft) d	(A v C) SD v C	31.4	0.409	12.1	0.777
	(B v C) G v C	79.7	0.036	22.5	0.585
	(A v B) SD v G	−48.3	0.202	−10.4	0.806
Weight (lbs) d	(A v C) SD v C	−0.44	0.676	1.50	0.305
	(B v C) G v C	−1.27	0.212	−1.72	0.227
	(A v B) SD v G	0.84	0.412	3.22	0.026

The total Sickness Impact Profile score and the physical and psychosocial dimension scores are not included as no significant findings between groups were found at 12 and 18 month follow-up.

^b(A) SD = Self-Directed Format, (B) G = Group Format, (C) C = Control Group.

^cAnalysis utilized log-transformed normal regression

^dAnalysis utilized normal regression