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. 2012 Apr 20;7(4):e35559. doi: 10.1371/journal.pone.0035559

Figure 1. Decision tree for an individual tested for Alzheimer's disease (AD).

Figure 1

Possible outcomes of the testing procedure are depicted as a function of the individual's health status for: (a) The primary scenario (testing of over-70 patients consulting for dementia symptoms). (b) The “screen and treat” scenario (systematic screening of the over-60 population). Depending on the investigated strategy, the generic “diagnostic test” mentioned in the trees may be standard diagnosis, standard MRI or MRI+CLP. When AD is diagnosed, the imaging procedures are followed by a cognition test (MMSE) in order to determine the disease stage. No test is performed in severe AD patients, who are assumed to be diagnosed directly.