Table 3.
Effect of ULEtOH on the concentration (ng/g tissue) of monoamines and their metabolites in the hippocampus of mice brain.
Groups | Hippocampus (ng/g tissue) | |||||
---|---|---|---|---|---|---|
NE | MHPG | DA | DOPAC | 5-HT | 5-HIAA | |
Normal | 581.57 ± 25.89 | 640.84 ± 44.27 | 713.98 ± 27.06 | 639.43 ± 49.15 | 638.07 ± 31.74 | 613.67 ± 78.51 |
Control versus FST | 183.67 ± 24.01# | 210.34 ± 22.72## | 275.21 ± 34.86## | 268.46 ± 26.14 | 113.72 ± 25.71### | 192.77 ± 15.70## |
Imipramine 10 mg/kg | 851.76 ± 96.22*** | 682.1 ± 31.39*** | 633.56 ± 63.63 | 445.35 ± 94.67 | 898.71 ± 35.47*** | 1028.46 ± 75.43*** |
ULEtOH 0.125 g/kg | 431.38 ± 52.01 | 386.16 ± 27.86 | 435.43 ± 63.16 | 360.87 ± 107.15 | 201.48 ± 73.29 | 354.73 ± 91.78 |
ULEtOH 0.25 g/kg | 510.95 ± 52.67** | 515.38 ± 97.48** | 539.59 ± 72.49 | 432.42 ± 67.79 | 229.74 ± 55.82 | 509.97 ± 44.55* |
ULEtOH 0.5 g/kg | 824.21 ± 71.69*** | 735.31 ± .84*** | 612.29 ± 84.59 | 532.09 ± 42.28 | 381.89 ± 10.25** | 665.73 ± 42.55** |
Value were the mean ± SEM (n = 6). # P < 0.05, ## P < 0.01, ### P < 0.001 as compared with the normal group.
*P < 0.05,**P < 0.01,***P < 0.001 as compared with the control group (one-way ANOVA following by Bonferroni's test).