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. 2012 Apr 20;7(4):e34401. doi: 10.1371/journal.pone.0034401

Figure 2. Phylogenetic analysis of sequences of representative Chinese measles viruses, compared to the WHO reference sequences.

Figure 2

These trees are based on the WHO standard sequence window within the N gene. Panel A. Phylogenetic tree of 87 representative measles isolates from China during 1993–2008 compared to the WHO reference sequences for each genotype. Sequences from Chinese viruses of H1a cluster from 1993–2008 are indicated by blue and sequences from Chinese viruses of H1b cluster from 1994–2005 are indicated by fluorescence green, and WHO reference strains are indicated by red. All isolates from China, including 3 WHO reference strains(Hunan.China93-7/H1, Beijing.China94-1/H2, MVi/Menglian.Yunnan.CHN/47.09/d11), are indicated by solid rounded dots. Panel B. Phylogenetic tree of 5 measles vaccine viruses from China compared to the A genotype strains of Edmonston wild type and other vaccine strains used worldwide. Sequences from viruses isolated in China are indicated by blue, and A genotype wild type Edmonston strain is indicated by red. Two Chinese measles vaccines are indicated by green solid triangles.