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. 2012 Apr 20;7(4):e34036. doi: 10.1371/journal.pone.0034036

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(A) Schematic of DD-tagged mutants of PFK2/FBPase2. (B and C) Western blots of islets transduced with DD-PFK2 and DD-FBPase2 truncations mutants (B), or DD-tagged phosphatase-dead PFK2/FBPase2 (DD-H259A) and kinase-dead PFK2/FBPase2 (DD-T55V) point mutants (C), treated with either vehicle (0.1% DMSO) or 1 µM Shield1, and visualized with an anti-DD antibody. Representative of three independent experiments (50 islets per treatment).