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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Mol Cancer Res. 2011 Dec 7;10(2):250–258. doi: 10.1158/1541-7786.MCR-11-0287

Figure 2. Functional validation of the role of the E6 PDZ-binding domain in adult mice strains.

Figure 2

Two PDZ-containing E6 targets (Dlg1 and Scribble) were evaluated in dorsal skin biopsies from 4-months-old mice by immunohistochemistry (A) or immunoblotting (B). As we show in graphs, only the K14E6 strain significantly suppressed the Dlg1 or Scribble (Scrib) proteins compared to K14E6ΔPDZ and the non-transgenic (NTG) mice. Magnification: 40X. Ep = Epidermis. Dashed line = Basal membrane. Scale bar = 20 μm.