Table 1.

Donor Characteristics Used in the Kidney Donor Profile Index^*

Donor Characteristics	Hazard Ratio*	95% CI*	P*
Age
Age-40 yr (applies to all ages)	1.013	1.011–1.015	< 0.0001
Age-18 yr (applies to age < 18 yr)	0.98	0.97–0.99	0.0033
Age-50 yr (applies to age > 50 yr)	1.011	1.005–1.016	0.0001
African American race (versus white)	1.20	1.13–1.27	< 0.0001
Hypertensive	1.13	1.08–1.19	< 0.0001
Diabetic	1.14	1.04–1.24	0.0040
Creatinine
Scr-1 (applies to all Scr values)	1.25	1.17–1.33	< 0.0001
Scr-1.5 (applies if Scr > 1.5 only)	0.81	0.74–0.89	< 0.0001
Cause of death CVA	1.09	1.04–1.14	0.0002
Height (per 10 cm increase)	0.96	0.94–0.97	< 0.0001
Weight (per 5 kg increase below 80 kg)	0.98	0.97–0.99	0.0003
Donation after cardiac death	1.14	1.02–1.28	0.0246
Hepatitis C	1.27	1.13–1.43	< 0.0001

CI, confidence interval; CVA, cerebrovascular accident; Scr, serum creatinine.

^*Derived from the Kidney Donor Risk Index (KDRI) developed by Rao et al (12) assuming an average transplant (2 mismatches at the HLA-B locus, 1 mismatch at the HLA-DR locus, 20 hours cold ischemia time, not en bloc or double transplant).

Calculation: Kidney Donor Profile Index = exp(−0.0194 × I[age < 18yr] × [age − 18yr] + 0.0128 × [age − 40yr] + 0.0107 × I[age > 50yr] + 0.179 × I[race = African American] + 0.126 × I [hypertensive] + 0.130 × I[diabetic] + 0.220 × [Scr − 1mg/dL] − 0.209 × I[Scr>1.5mg/dL] × [Scr −1.5mg/dL] + 0.0881 × I[cause of death = CVA] − 0.0464 × [{height − 170cm}/10] − 0.0199 × I[weight < 80 kg] × [{weight − 80kg}/5] + 0.133 × I[donation after cardiac death] + 0.240 × I[hepatitis C] − 0.0766 where I is equal to 1 if the condition is true and I is equal to 0 if the condition is false.