Table 2.
Donor Characteristics | Hazard Ratio | 95% CI | P |
---|---|---|---|
Age, yr | |||
< 40 | 1 | ||
40–49 | 1.17 | 1.08–1.26 | 0.0002 |
50–59 | 1.32 | 1.21–1.43 | < 0.0001 |
60–69 | 1.53 | 1.39–1.68 | < 0.0001 |
> 70 | 1.65 | 1.46–1.87 | < 0.0001 |
African American race (versus white) | 1.19 | 1.10–1.29 | < 0.0001 |
Height (per 10 cm decrease) | 1.07 | 1.04–1.09 | < 0.0001 |
Cause of death, CVA | 1.16 | 1.08–1.24 | < 0.0001 |
Cause of death other | 1.2 | 1.03–1.40 | 0.018 |
Donation after cardiac death | 1.51 | 1.19–1.91 | 0.0006 |
Partial/split liver | 1.52 | 1.27–1.83 | < 0.0001 |
CI, confidence interval; COD, cause of death; CVA, cerebrovascular accident; DCD, donation after cardiac death.
Table modified from Feng et al (19). Data from the Scientific Registry of Transplant Recipients for adult deceased donor liver transplants 1998–2002 were used to identify donor factors associated with allograft failure, after adjustment for recipient and transplant factors. The final Liver Donor Risk Index model also includes regional and national share and cold ischemia time.
Calculation: Liver Donor Risk Index = exp[(0.154 if 40≤ age <50) + (0.274 if 50 ≤ ge <60) + (0.424 if 60≤ age <70) + (0.501 if 70 ≤ age) + (0.079 if COD = anoxia) + (0.145 if COD = CVA) + (0.184 if COD = other) + (0.176 if race = African American) + (0.126 if race = other) + (0.411 if DCD)+(0.422 if partial/split)+(0.066 ((170–height)/10))+(0.105 if regional share)+(0.244 if national share)+(0.010×cold ischemia time)].