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. 2012 Apr 12;2012:756284. doi: 10.1155/2012/756284

Table 2.

Top significant pathways and functions.

ID Molecules in network Score Focus molecules Top functions
1 Akt, Ap1, ARG2, ASGR1, ATF3, CCL8, CCL24, CLDN11, CNN1, CREM, CXCL1, DLL4, ERK1/2, FABP4, FASN, G0S2, hCG, Histone h3, HSPA1A/HSPA1B, IL13, IL12A, MAPKAP1, NFkB (complex), NPR3, Nr1h, NR4A3, PCK1, PDGF, PPP1R15A, RCAN1, RET, RGS2, SCD, SDC4, TNFRSF12A 57 27 Cellular growth and proliferation, cellular movement, lipid metabolism

2 Aconitase, ANKRD1, AP2B1, APCS, ASPM, BLNK, CA12, CDX2, DGAT2, EFNA3, ENPP1, FCGR3A, GADD45G, HAS1, HDGF, HNF1A, HTT, IFRD1, IgG, IL1B, ITPA, KIF20A, NGEF, PFK, PPL, RARA, RNA polymerase II, S100G, SERPING1, SGK2, SIM1, SOAT2, TGFB1, UGT1A8, YY1 21 13 Embryonic development, reproductive system development and function, nutritional disease

3 ABLIM, ACP2, ACSL5, ADCY9, ARPC1A, ATPIF1, CIDEC, CREBBP, DUSP3, DYRK3, FBP2, FSH, GLUL, GNLY, HGD, HOXB6, ING2, LEP, Lh, LHCGR, LOC81691, NR2F1, NR3C1, NR5A1, P4HA2, PDLIM3, PLCL1, POP5, PRKX, RAB5C, RGS5, RGS16, SREBF1, THRSP, TLK1 11 8 Drug metabolism, endocrine system development and function, lipid metabolism

4 NAALAD2, RORA 2 1 Amino acid metabolism, small molecule biochemistry, gene expression

5 FIGLA, TEKT1 2 1 Cell cycle, reproductive system development and function, cell death

6 ZHX1, ZHX3 2 1 Gene expression

7 AGTR1, HSPA6, RFWD2 2 1 Cardiovascular system development and function, organ morphology, organismal injury and abnormalities

8 AHR, GPI, STEAP4 2 1 Cell cycle, cell morphology, cell-to-cell signaling and interaction

9 CBX4, HOXA2, MBD1, MEOX1 2 1 Gene expression, embryonic development, organismal development

10 FBL, NFE2, PSMD14, STMN1, TUBB1 2 1 Cell morphology, hematological system development and function, inflammatory response

11 DMD, SGCA, SGCB, SGCD, SGCE, SGCG 1 1 Developmental disorder, genetic disorder, skeletal and muscular disorders