Table 2.
Changes in BP control, SBP and DBP within and between intervention and standard care groups with missing data replaced using last value carried forward
| Standard care group (n=21 704) |
Intervention group (n=9877) |
Difference (95% CI) between groups (intervention group − control group) |
|||||||||
| n (%) or mean (SD) | Difference* (95% CI) | SRM† | n (%) or mean (SD) | Difference* (95% CI) | SRM† | Unadjusted difference | p Value | SES‡ | Adjusted difference§ | p Value | |
| BP control | |||||||||||
| Baseline | 9854 (45.4) | 4341 (43.9) | |||||||||
| 4 months | 9657 (44.5) | −0.9 (−1.5 to −0.3) | 4547 (46.0) | 2.1 (1.2 to 2.9) | 1.5 (0.4 to 2.7) | 0.011 | |||||
| 9 months | 9469 (43.6) | −1.8 (−2.4 to −1.2) | 4614 (46.7) | 2.8 (1.9 to 3.6) | 3.1 (1.9 to 4.3) | <0.001 | |||||
| 1 year | 9457 (43.6) | −1.8 (−2.5 to −1.1) | 4880 (49.4) | 5.5 (4.4 to 6.5) | 5.8 (4.6 to 7.0) | <0.001 | 1.3 (1.1 to 1.6)¶ | 0.003 | |||
| SBP (mm Hg) | |||||||||||
| Baseline | 138.1 (13.6) | 138.7 (13.7) | |||||||||
| 4 months | 138.3 (13.6) | 0.3 (0.1 to 0.4) | −0.03 | 138.3 (13.7) | −0.4 (−0.5 to −0.2) | 0.04 | 0.0 (−0.3 to 0.3) | 0.95 | 0.00 | ||
| 9 months | 138.5 (13.1) | 0.4 (0.3 to.0.5) | −0.04 | 137.9 (13.1) | −0.8 (−1.0 to −0.6) | 0.09 | −0.6 (−0.9 to −0.3) | <0.001 | 0.05 | ||
| 1 year | 138.6 (13.8) | 0.5 (0.3 to 0.7) | −0.04 | 136.7 (13.3) | −2.0 (−2.3 to −1.8) | 0.16 | −1.9 (−2.2 to −1.6) | <0.001 | 0.14 | −2.1 (−3.3 to −0.8) | 0.001 |
| DBP (mm Hg) | |||||||||||
| Baseline | 79.4 (8.3) | 79.5 (8.9) | |||||||||
| 4 months | 78.9 (8.3) | −0.4 (−0.5 to −0.4) | 0.07 | 78.7 (9.0) | −0.8 (−0.9 to −0.7) | 0.14 | −0.2 (−0.4 to −0.0) | 0.023 | 0.03 | ||
| 9 months | 78.0 (8.1) | −0.4 (−0.5 to −0.3) | 0.07 | 78.6 (8.7) | −0.9 (−1.0 to −0.8) | 0.15 | −0.4 (−0.6 to −0.2) | <0.001 | 0.05 | ||
| 1 year | 78.6 (8.5) | −0.7 (−0.8 to −0.6) | 0.09 | 77.9 (9.0) | −1.6 (−1.7 to −1.4) | 0.21 | −0.7 (−0.9 to −0.5) | <0.001 | 0.08 | −0.9 (−1.3 to −0.5) | <0.001 |
Mean differences are shown for quantitative outcomes and percentage differences for dichotomous outcomes. Differences were calculated between follow-up measurements and baseline measurements.
SRM: standardised response mean was calculated as the mean change by the SD of the change.
SES: standardised effect size was calculated as the mean difference between intervention and control groups divided by the SD of the control measurement. A positive SRM or SES denotes improvement; a negative one denotes worsening of some clinical measurements.
Estimated with a mixed-effects model considering primary healthcare team as random effect. Mean differences are shown for quantitative outcomes and ORs for dichotomous outcomes. Adjusted for age at baseline, sex, number of antihypertensive drugs, comorbidity, cardiovascular event and baseline measurement.
Value is OR (95% CI).
BP, blood pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure.