Fig. 3.

Sex- and microvessel-sensitive changes in Ps to PSA in response to adenosine (Ado, 10⁻⁵ M). The paired mean permeability response ($P_{\mathrm{s}}^{\mathrm{Ado}}∕P_{\mathrm{s}}^{\mathrm{C}}$, where C is control) to a minimum of 5 min of suffusion with Ado is shown for PSA in arterioles (left) and venules (right) isolated from hearts of female (open bars) and male (shaded bars) pigs. Data are means ± SE. *P < 0.05, significant changes in permeability from basal levels. Significant differences also exist in direction and magnitude of responses with sex (**P < 0.01) and vessel type in females (***P < 0.01).