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. Author manuscript; available in PMC: 2013 Feb 7.
Published in final edited form as: J Am Coll Cardiol. 2012 Feb 7;59(6):616–626. doi: 10.1016/j.jacc.2011.10.881

Figure 9.

Figure 9

Representative correlation between in vivo MRI and the presence of MDA epitopes. The aorta was imaged in vivo prior to and 48 hours after the administration of 0.05 mmol Mn/Kg MDA2 labeled micelles. The mouse was sacrificed immediately after imaging and the immunohistology performed. The aorta was opened longitudinally and stained with Sudan (red color). The yellow line in the Sudan stained aorta reflects the area of MR imaging and histological assessment for MDA epitopes. Strong MR signal was observed in regions exhibiting plaque deposition and the presence of MDA-lysine epitopes (red).