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. Author manuscript; available in PMC: 2013 Apr 4.
Published in final edited form as: J Am Chem Soc. 2012 Mar 26;134(13):5794–5797. doi: 10.1021/ja301612y

Table 1.

Catalytic asymmetric Suzuki cross-couplings of unactivated alkyl electrophiles to generate carbamate-protected amines.a

graphic file with name nihms366375t1.jpg

entry electrophile R2 ee (%) yield (%)b
1 graphic file with name nihms366375t2.jpg graphic file with name nihms366375t3.jpg 91 56
2 graphic file with name nihms366375t4.jpg graphic file with name nihms366375t5.jpg 90 83
3 graphic file with name nihms366375t6.jpg graphic file with name nihms366375t7.jpg 90 74
4 graphic file with name nihms366375t8.jpg n-Hex 90 56
5 graphic file with name nihms366375t9.jpg graphic file with name nihms366375t10.jpg 80 66
a

All data are the average of two experiments.

b

Yield of purified product.