Table 4.
Follow-up period | Favorable variables | Reference | Response R0a | Response R1a | ||||
---|---|---|---|---|---|---|---|---|
|
|
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OR | 95% CI | P | OR | 95% CI | P | |||
M6 | Age ≤50 years | Age >50 years | 1.28 | 0.57–2.86 | 0.542 | 1.44 | 0.76–2.72 | 0.262 |
Stages A or B | Stage C | 0.91 | 0.47–1.76 | 0.782 | 0.98 | 0.58–1.63 | 0.932 | |
Baseline CD4 cell count of ≥200/mm3 | Baseline CD4 cell count of <200/mm3 | 2.57 | 1.44–4.57 | 0.001 | 0.78 | 0.46–1.32 | 0.350 | |
Good adherence | Incomplete adherence | 0.70 | 0.20–2.41 | 0.576 | 0.76 | 0.28–2.11 | 0.603 | |
M12 | Age ≤50 years | Age >50 years | 0.76 | 0.30–1.94 | 0.568 | 1.12 | 0.62–2.02 | 0.709 |
Stages A or B | Stage C | 0.76 | 0.35–1.69 | 0.509 | 1.08 | 0.66–1.77 | 0.747 | |
Baseline CD4 cell count of ≥200/mm3 | Baseline CD4 cell count of <200/mm3 | 3 | 1.45–6.26 | 0.003 | 1.20 | 0.75–1.94 | 0.446 | |
Good adherence | Incomplete adherence | 0.15 | 0.06–0.39 | <0.001 | 0.53 | 0.24–1.14 | 0.105 |
Notes:
Responses R0 and R1 were compared to response R2; P < 0.05 was considered significant.
Abbreviations: CI, confidence interval; OR, odds ratio; R0, stabilization or decrease of CD4 cell count compared to the baseline value; R1, suboptimal immunological response; R2, optimal immunological response.