Table 5.
Follow-up period | Favorable variables | Reference | Response R0a | Response R2a | ||||
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|
|
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OR | 95% CI | P | OR | 95% CI | P | |||
M18 | Age ≤50 years | Age >50 years | 0.91 | 0.31–2.69 | 0.867 | 1.19 | 0.67–2.12 | 0.550 |
Stages A or B | Stage C | 0.53 | 0.22–1.29 | 0.16 | 0.94 | 0.58–1.51 | 0.794 | |
Baseline CD4 cell count of ≥200/mm3 | Baseline CD4 cell count of <200/mm3 | 5.14 | 2.22–11.89 | <0.001 | 1.14 | 0.71–1.82 | 0.587 | |
Good adherence | Incomplete adherence | 0.28 | 0.09–0.83 | 0.022 | 2.44 | 0.93–6.38 | 0.070 | |
M24 | Age ≤50 years | Age >50 years | 0.53 | 0.17–1.62 | 0.267 | 0.97 | 0.54–1.76 | 0.931 |
Stages A or B | Stage C | 0.45 | 0.17–1.19 | 0.107 | 0.96 | 0.58–1.58 | 0.873 | |
Baseline CD4 cell count of ≥200/mm3 | Baseline CD4 cell count of <200/mm3 | 2.71 | 1.06–6.94 | 0.037 | 0.82 | 0.50–1.32 | 0.413 | |
Good adherence | Incomplete adherence | 0.32 | 0.12–0.86 | 0.023 | 5.82 | 2.24–15.14 | <0.001 |
Notes:
Responses R0 and R2 were compared to response R1; P < 0.05 was considered significant.
Abbreviations: CI, confidence interval; OR, odds ratio; R0, stabilization or decrease of CD4 cell count compared to the baseline value; R1, suboptimal immunological response; R2, optimal immunological response.