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. Author manuscript; available in PMC: 2013 Feb 17.
Published in final edited form as: Circ Res. 2012 Jan 19;110(4):560–568. doi: 10.1161/CIRCRESAHA.111.256362

Figure 6. TXNIP suppresses KLF2 promoter activity.

Figure 6

(A) Various deletion constructs (-924 bp, -157 bp and -78 bp) of the KLF2 promoter were co-transfected with TXNIP-GFP or control plasmid into HUVEC. After 24 h of transfection, cells were harvested and the luciferase activities were measured. (B and C) HUVEC were co-transfected with either TXNIP-GFP or control plasmid, and -924 bp (B) or -157 bp (C) KLF2 promoter reporter gene construct. After 18 h of incubation, cells were exposed to s-flow or kept at static condition for 6 h before harvest for luciferase assay. Results are expressed as mean ± SD of 3 independent experiments. *P<0.05.