Figure 1.
Predicted secondary structure and conservation of the human HBII-180 box C/D snoRNAs. (A) The characteristic features of the box C/D snoRNA HBII-180C are illustrated including conserved C and D motifs indicated by orange and cyan boxes, respectively. The guide region (complementary to 28 S rRNA) is displayed in pink and the position of the M-box region is shown in blue. (B) Screenshot of the UCSC Genome Browser (10) displaying the mammalian conservation and alignment of HBII-180C, encoded in chromosome 19 in an intron of gene C19orf48.
