Table 1.
Total number of cells in lymph nodes in DA and E3 naïve rats and rats 8 days after pristane injection
| Total cell number (millions) | ||||||
| Cell type | DA day 0* | E3 day 0* | Difference between DA and E3 on day 0** | DA day 8 | E3 day 8 | Difference between DA and E3 on day 8** |
| Leucocytes | 10 ± 1.5 | 8 ± 0.79 | NC, P < 0.1 | 27 ± 3.6 | 45 ± 21 | NC, P < 0.3 |
| Granulocytes | 0.034 ± 0.01 | 0.052 ± 0.01 | D, P < 0.04 | 0.48 ± 0.14 | 0.92 ± 0.62 | NC, P < 0.5 |
| B cells | 1.8 ± 0.64 | 2.3 ± 0.29 | NC, P < 0.25 | 6.3 ± 1.2 | 24 ± 13 | D, P < 0.03 |
| αβ T cells | 7.9 ± 0.7 | 5.4 ± 0.3 | I, P < 0.02 | 20 ± 1.3 | 19 ± 2.8 | NC, P < 1 |
| CD4+/αβ T cells | 6.2 ± 0.5 | 4.3 ± 0.2 | MI, P < 0.08 | 14 ± 0.9 | 13 ± 1.7 | NC, P < 0.3 |
| CD8+/αβ T cells | 2.2 ± 0.2 | 1.7 ± 0.1 | NC, P < 0.2 | 6.1 ± 0.7 | 7.5 ± 1.4 | NC, P < 0.3 |
| γδ T cells | 0.024 ± 0.013 | 0.038 ± 0.0086 | MD, P < 0.1 | 0.048 ± 0.018 | 0.24 ± 0.16 | D, P < 0.03 |
| NK cells | 0.095 ± 0.034 | 0.12 ± 0.01 | NC, P < 0.4 | 0.46 ± 0.07 | 1.51 ± 1.0 | NC, P < 0.2 |
| NK T cells | 0.054 ± 0.019 | 0.12 ± 0.024 | D, P < 0.02 | 0.19 ± 0.035 | 2 ± 1.2 | D, P < 0.03 |
*Mean total cell number (in millions) ± standard deviation (SD) determined by fluorescence activated cell sorting (FACS) analysis. Data based on three DA and E3 naïve rats and three DA and E3 rats 8 days after pristane injection. **Difference in cell number: DA versus E3. P values calculated by Mann–Whitney nonparametric test. D, decrease; I, increase; MD, marginally decrease; MI, marginally increase; NC, no change.