Skip to main content
. 2010 Aug;24(6):996–1007. doi: 10.1016/j.bbi.2010.04.004

Fig. 1.

Fig. 1

Systemic poly I:C induces anti-viral transcripts in the brain. Expression of mRNA for IFNβ, IFNα, TLR3 and RIG-I in the hippocampus (a) or hypothalamus (b) of NBH and ME7 animals (6 hours post-challenge, 18 weeks post-inoculation) treated once with saline or poly I:C (12 mg/kg). Data are expressed as mean ± SEM, n = 3 for NBH + saline and n = 5 for all other groups. Significant interaction of poly I:C and ME7 in the hippocampus by two-way ANOVA is indicated by ∗p < 0.05 and ∗∗p < 0.01. Interactions between factors were not observed in the hypothalamus and main effects of poly I:C are described in the text.