Table 2.
Immunohistochemical quantification.
IHC label | NBH + poly I:C | ME7 + saline | ME7 + poly I:C |
---|---|---|---|
IBA-1 | 48 ± 5 | 172 ± 15∗ | 172 ± 14∗ |
IL-1β | ND | ND | 49 ± 29∗ |
TUNEL | 1 ± 1 | 6 ± 1∗ | 12 ± 3∗ |
IL-1β and TUNEL counts were performed in the hippocampus and thalamus in 10 μm coronal sections, 3 and 15 h, respectively after poly I:C administration. IBA-1 counts were performed in a 0.62 × 0.47 mm region of the hippocampus. ND signifies that positive cells were not detectable. Significant differences to NBH + poly I:C controls by one-way ANOVA and Bonferroni post hoc tests are signified by ∗p < 0.05.