Fig. 4.

The discrete network embedded within its distinct perfusion territory on which a comparison of a Poiseuille flow model and a continuum model based on Darcy's law is made (upper left). Volume-averaged pressure, plotted on five axial slices, from the Poiseuille flow model (upper right) is matched well by the static Darcy model (lower right). Comparison with the strictly hierarchical model (lower left) shows that removing the connections between non-neighbouring compartments results in an over-estimation of pressure.