Figure 5. PTH1R levels in acinar and stellate cells treated with cerulein or ethanol.
(A) Primary (10) acinar and stellate cells, AR42J (acinar) and iPSCc3 (stellate) cells were treated with cerulein (10−7 M) or ethanol (50 mM) for 4 h. Saos-2 cells were used as positive control. PTH1R mRNA levels were measured by reverse transcription/real-time PCR. Values are expressed relative to the Saos-2 value, set arbitrarily at 100. Each bar is the mean ± SEM of three independent experiments. (B and C) IHC analysis for PTH1R in cells treated with cerulein (CR) or ethanol (EtOH) as described in (A). − = no treatment. IgG = antibody control. The panels other than IgG were immunostained with anti-PTH1R antibody.