Table 4. SNPs associated with acquisition of natural influenza post-vaccination.
SNPs associated at p<9.5×10−5 for six cases and 55 controls are shown below.
| Chromosome | rs number | Base position | Alleles | Frequency among cases |
Frequency among controls |
p-value | Candidate gene (SNP type) |
|---|---|---|---|---|---|---|---|
| 7 | rs6593122 | 54149426 | A/G | 0.75 | 0.11 | 3.91E-06 | |
| 7 | rs2177549 | 54151555 | A/C | 0.75 | 0.11 | 3.91E-06 | |
| 7 | rs10247013 | 54156299 | G/A | 0.75 | 0.15 | 2.44E-05 | |
| 17 | rs317397 | 29200759 | G/A | 0.83 | 0.21 | 2.93E-05 |
ACCN1 (intron) |
| 17 | rs317400 | 29201307 | C/A | 0.83 | 0.21 | 2.93E-05 |
ACCN1 (intron) |
| 9 | rs4615664 | 22865745 | G/A | 0.67 | 0.11 | 4.35E-05 | |
| 8 | rs16917360 | 96196308 | A/G | 0.33 | 0 | 5.64E-05 | |
| 20 | rs7263 | 19954368 | G/A | 0.33 | 0 | 5.64E-05 |
NAT5 (synonymous) |
| 20 | rs16981483 | 19979667 | A/G | 0.33 | 0 | 5.64E-05 |
C20orf26 (5′ flanking) |
| 1 | rs4573512 | 14616559 | G/A | 0.92 | 0.31 | 6.24E-05 | |
| 1 | rs2744690 | 14010388 | A/C | 0.67 | 0.12 | 6.79E-05 |
PRDM2 (intron) |
| 8 | rs2935762 | 1.1E+08 | G/A | 0.83 | 0.24 | 7.57E-05 | |
| 8 | rs1391200 | 1.1E+08 | G/A | 0.83 | 0.24 | 7.57E-05 | |
| 7 | rs2330668 | 54156583 | A/G | 0.75 | 0.17 | 7.59E-05 | |
| 1 | rs4128690 | 14617468 | A/G | 0.92 | 0.32 | 8.11E-05 | |
| 4 | rs6848312 | 6887563 | C/A | 0.50 | 0.05 | 8.39E-05 |
KIAA0232 (intron) |
| 3 | rs11709947 | 1.25E+08 | G/A | 1.0 | 0.43 | 8.63E-05 |
MYLK (intron) |
| 9 | rs4465047 | 22862158 | C/A | 0.58 | 0.08 | 9.44E-05 | |
| 9 | rs1463014 | 22934927 | G/A | 0.58 | 0.08 | 9.44E-05 |