Table IV.

Breakdown of study costs (efficacy studies only)

Contract research organization	70.5%
Site management	25.1
Project management	21.1
Travel	6.2
Data management	4.9
Manuscript preparation	4.9
Pre-study preparation	4.2
Randomization	2.4
Other	1.7
Sponsor	19.0%
Investigator site	10.9%
Central laboratory	1.7%

Sponsor costs are net pharmaceutical costs and represent the net costs of outsourcing clinical studies (external pharmaceutical costs) versus performing clinical studies internally (internal pharmaceutical costs).