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. Author manuscript; available in PMC: 2012 Apr 25.
Published in final edited form as: Cell Rep. 2012 Feb 23;1(2):110–117. doi: 10.1016/j.celrep.2011.12.001

Figure 2.

Figure 2

MYC regulates SRSF1 expression and alternative splicing SRSF1 Target Genes. (A) RT-PCR and (B) Immunoblotting of SRSF1 from IMR90-ER.MYC or IMR90-ER.MYCΔMBII cells induced with 4-OHT. Error bars, s.d.; n=3; t-test **P<0.01. (C) RT-PCR of MKNK2 and TEAD1 mRNA isoforms in IMR90-ER.MYC cells induced with 4-OHT, with or without SRSF1 knockdown. IMR90 cells overexpressing SRSF1 or hnRNPA1 are shown as controls. Error bars, s.d.; n=3, *P<0.05. See also Figure S2.