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Urinary 8-OH-dG levels corrected by creatinine (ng/mg) at each time point after i.p. administration of 3 mg metal oxide nanoparticles. The data show the ratio of 8-OH-dG levels at each time point to that at zero time, because each mouse had a different 8-OH-dG level before administration. Each value represents the average of 3 mice ± SE. *indicates significantly higher levels as compared to the control, corresponding to p<0.05.
