Table 1.
Characteristics of women according to migraine in the Women’s Health Study (n=31,370)
No Migraine (n=24,513) |
Any migraine (n=6,857) |
p-value* | |
---|---|---|---|
Demographic information | |||
Mean age, yrs (SD) | 63.9 (7.1) | 62.5 (6.3) | <0.01 |
Ethnicity White |
23,203 (95.4) |
6,482 (95.5) |
0.83 |
Geographic location Northeast Southeast Midwest West |
4,715 (19.3) 5,568 (22.8) 8,930 (36.5) 5,262 (21.5) |
1,344 (19.6) 1,646 (24.0) 2,368 (34.6) 1,491 (21.8) |
0.02 |
Covariates | |||
BMI, kg/m2 <25 25–29.9 ≥30 |
9,976 (41.4) 8,241 (34.2) 5,911 (24.5) |
2,646 (39.2) 2,360 (35.0) 1,744 (25.8) |
<0.01 |
History of diabetes | 1,841 (7.5) | 501 (7.3) | 0.57 |
History of hypertension | 11,715 (47.8) | 3,508 (51.2) | <0.01 |
History of cholesterol ≥240mg/dl | 13,112 (53.5) | 3,974 (58.0) | <0.01 |
Alcohol consumption Rarely/never 1–3 drinks per month 1–6 drinks per week ≥1 drink/day |
10,386 (42.6) 2,746 (11.3) 8,307 (34.1) 2,924 (12.0) |
3,121 (45.8) 859 (12.6) 2,208 (32.4) 631 (9.3) |
<0.01 |
Smoking Status Never Past Current |
12,242 (50.6) 9,935 (41.1) 2,018 (8.3) |
3,579 (53.1) 2,606 (38.6) 559 (8.3) |
<0.01 |
Exercise Rarely/never <1/week 1–3 times/week ≥ 4 times/week |
9,386 (38.3) 4,766 (19.5) 7,628 (31.1) 2,725 (11.1) |
2,584 (37.7) 1,517 (22.1) 2,093 (30.5) 659 (9.6) |
<0.01 |
Family history of myocardial infarction | 4,131 (16.9) | 1,298 (19.0) | <0.01 |
Major CVD | 376 (1.5) | 117 (1.7) | 0.31 |
Postmenopausal Hormone Use Never Past Current |
5,514 (23.4) 5,998 (25.5) 12,011 (51.1) |
1,089 (16.6) 1,657 (25.3) 3,815 (58.2) |
<0.01 |
Menopausal Status Premenopausal Postmenopausal Biologically uncertain Unclear |
417 (1.7) 22,012 (91.5) 1,397 (5.8) 235 (0.99) |
110 (1.7) 5,917 (88.5) 589 (8.8) 69 (1.03) |
<0.01 |
Number of pregnancies 0 1–2 3–4 5–6 |
3,077 (12.6) 9,202 (37.7) 9,386 (38.4) 2,759 (11.3) |
782 (11.4) 2,661 (38.9) 2,718 (39.8) 677 (9.9) |
<0.01 |
History of depression | 2,863 (11.7) | 1,237 (18.0) | <0.01 |
History of Parkinson’s disease | 934 (3.9) | 281 (4.2) | 0.25 |
Iron supplementation use | 107 (0.4) | 31 (0.5) | 0.86 |
Fatigue | 8,644 (35.4) | 3,063 (44.9) | <0.01 |
Values are number of people (%) unless denoted otherwise.
p-value from t-test for continuous variables and chi-square test for categorical variables.