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Human mitochondrial DNA replication proteins
| Enzyme | Size | Human Chromosome |
|---|---|---|
| DNA polymerase γ | ||
| POLG | 140 kDa | 15q25 |
| POLG2 | 55 kDa | 17q23-24 |
| Single-Stranded DNA binding protein (mtSSB) | 15 kDa | 7q34 |
| Helicase | ||
| C10orf2 (Twinkle) | 77 kDa | 10q24 |
| Topoisomerases | ||
| Topo Imt | 67 kDa | 8q24.3 |
| Topo IIIα | 112 kDa | 17p12-11.2 |
| RNase H1 | 32 kDa | 19p13.2 |
