Table 1.
Group | Mean arterial blood pressure (mm Hg) | ||||||
---|---|---|---|---|---|---|---|
Baseline | 1 hr | 2 hr | 30 min after placebo(last value before death) or sulfanegen Rx | 1 hr after placebo or sulfanegen Rx | 2 hr after placebo or sulfanegen Rx | 3 hr after placebo or sulfanegen Rx | |
Placebo | 88±7 | *67±5 | *66±21 | *26±5 | Pigs died | ||
Sulfanegen | 94±14 | *77±10 | *81±15 | *69±7 | 88±14 | 93±18 | 90±13 |
Heart Rate (bpm) | |||||||
Placebo | 104±19 | *149±13 | *155±24 | *60±19 | Pigs died | ||
Sulfanegen | 116±28 | *140±10 | *148±23 | *178±26 | *165±29 | 121±14 | 119±11 |
Mean pulmonary artery pressure (mm Hg) | |||||||
Placebo | 12±3 | *22±4 | *26±6 | *21±5 | Pigs died | ||
Sulfanegen | 16±3 | *22±4 | *29±2 | *21±5 | *28±5 | *22±5 | 15±2 |
Mean central venous pressure (mm Hg) | |||||||
Placebo | 5±2 | 6±4 | 7±3 | 7±2 | Pigs died | ||
Sulfanegen | 4±1 | 7±4 | 7±1 | 5±2 | *9±1 | 7±3 | 5±1 |
SNP = sodium nitroprusside
p < 0.05 vs baseline