Table 1.
Microsatellite Markers Associated with the Highest HLOD Scores
Marker | Location | HLODa | HLODb | NPL (P value)c |
---|---|---|---|---|
D1S235 | 1q42.3 | 1.87 | 1.52 | 1.025 (0.014) |
D1S304 | 1q43 | 1.74 | 1.41 | 0.990 (0.016) |
D3S1300 | 3p14.2 | 1.66 | 1.24 | 0.725 (0.033) |
D3S1595 | 3p12.1 | 1.11 | 1.10 | 0.916 (0.019) |
D9S159 | 9q34.11 | 2.71 | 2.29 | 1.707 (0.002) |
D9S1818 | 9q34.2 | 2.27 | 2.11 | 1.679 (0.002) |
D21S265 | 21q21.3 | 1.92 | 1.50 | 0.939 (0.018) |
Autosomal dominant model with penetrance of 1.
Autosomal dominant model with penetrance of 0.5.
NPL (nonparametric linkage statistic) and associated P values were calculated using the Kong and Cox linear model.